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American League
National League
Promotion ~ MLB (Play Offs)
Quarter-finals
Semi-finals
Final
2010 Main
American League
| Pl | W | L | PCT | |||
| 1 | Tampa Bay Rays | 162 | 96 | 66 | 802:649 | 0.593 |
| 2 | Minnesota Twins | 162 | 94 | 68 | 781:671 | 0.580 |
| 3 | Texas Rangers | 162 | 90 | 72 | 787:687 | 0.556 |
| 4 | New York Yankees | 162 | 95 | 67 | 859:693 | 0.586 |
| 5 | Boston Red Sox | 162 | 89 | 73 | 818:744 | 0.549 |
| 6 | Chicago White Sox | 162 | 88 | 74 | 752:704 | 0.543 |
| 7 | Toronto Blue Jays | 162 | 85 | 77 | 755:728 | 0.525 |
| 8 | Detroit Tigers | 162 | 81 | 81 | 751:743 | 0.500 |
| 9 | Oakland Athletics | 162 | 81 | 81 | 663:626 | 0.500 |
| 10 | Los Angeles Angels | 162 | 80 | 82 | 681:702 | 0.494 |
| 11 | Cleveland Guardians | 162 | 69 | 93 | 646:752 | 0.426 |
| 12 | Kansas City Royals | 162 | 67 | 95 | 676:845 | 0.414 |
| 13 | Baltimore Orioles | 162 | 66 | 96 | 613:785 | 0.407 |
| 14 | Seattle Mariners | 162 | 61 | 101 | 513:698 | 0.377 |
National League
| Pl | W | L | PCT | |||
| 1 | Philadelphia Phillies | 162 | 97 | 65 | 772:640 | 0.599 |
| 2 | San Francisco Giants | 162 | 92 | 70 | 697:583 | 0.568 |
| 3 | Atlanta Braves | 162 | 91 | 71 | 738:629 | 0.562 |
| 4 | Cincinnati Reds | 162 | 91 | 71 | 790:685 | 0.562 |
| 5 | San Diego Padres | 162 | 90 | 72 | 665:581 | 0.556 |
| 6 | St.Louis Cardinals | 162 | 86 | 76 | 736:641 | 0.531 |
| 7 | Colorado Rockies | 162 | 83 | 79 | 770:717 | 0.512 |
| 8 | Los Angeles Dodgers | 162 | 80 | 82 | 667:692 | 0.494 |
| 9 | Miami Marlins | 162 | 80 | 82 | 719:717 | 0.494 |
| 10 | New York Mets | 162 | 79 | 83 | 656:652 | 0.488 |
| 11 | Milwaukee Brewers | 162 | 77 | 85 | 750:804 | 0.475 |
| 12 | Houston Astros | 162 | 76 | 86 | 611:729 | 0.469 |
| 13 | Chicago Cubs | 162 | 75 | 87 | 685:767 | 0.463 |
| 14 | Washington Nationals | 162 | 69 | 93 | 655:742 | 0.426 |
| 15 | Arizona Diamondbacks | 162 | 65 | 97 | 713:836 | 0.401 |
| 16 | Pittsburgh Pirates | 162 | 57 | 105 | 587:866 | 0.352 |
Promotion ~ MLB (Play Offs)
2010 Play Offs
Quarter-finals
| 1 | Tampa Bay Rays | Texas Rangers | 2 : 3 |
| 2 | Minnesota Twins | New York Yankees | 0 : 3 |
| 3 | Philadelphia Phillies | Cincinnati Reds | 3 : 0 |
| 4 | San Francisco Giants | Atlanta Braves | 3 : 1 |
Semi-finals
| 1 | Texas Rangers | New York Yankees | 4 : 2 |
| 2 | Philadelphia Phillies | San Francisco Giants | 2 : 4 |
Final
| 1 | Texas Rangers | San Francisco Giants | 1 : 4 |
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