2021 Main
Group A
| Pts | W | L | N/R | Pts | |||
| 1 | South East Stars W | 6 | 5 | 1 | 0 | 860:787 | 21 |
| 2 | Southern Vipers W | 6 | 4 | 2 | 0 | 783:752 | 19 |
| 3 | Central Sparks W | 6 | 3 | 3 | 0 | 725:747 | 12 |
| 4 | Loughborough Lightning W | 6 | 0 | 6 | 0 | 683:765 | 0 |
Group B
| Pts | W | L | N/R | Pts | |||
| 1 | Western Storm W | 6 | 4 | 2 | 0 | 630:705 | 17 |
| 2 | Northern Diamonds W | 6 | 4 | 2 | 0 | 655:642 | 16 |
| 3 | Thunder W | 5 | 2 | 3 | 0 | 604:450 | 11 |
| 4 | Sunrisers W | 5 | 1 | 4 | 0 | 607:699 | 6 |
Promotion ~ Charlotte Edwards Cup Women (Play Offs: Final)
2021 Play Offs
Semi-finals
| 1 | South East Stars W | Bye | |
| 2 | Northern Diamonds W | Southern Vipers W | 135 : 117 |
Final
| 1 | South East Stars W | Northern Diamonds W | 139 : 138 |
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