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Promotion ~ Gamma Ethniki ~ Promotion Play~offs (Promotion ~ Play Offs: )
Relegation
North
South
Promotion ~ Football League
2020/21 Main
| Pl | W | D | L | Diff | Pts | |||
| 1 | Poseidonas Michanionas | 14 | 12 | 2 | 0 | 27:6 | 21 | 38 |
| 2 | Keravnos Anchelochori | 14 | 8 | 2 | 4 | 23:15 | 8 | 26 |
| 3 | Thermaikos FC | 14 | 8 | 1 | 5 | 24:18 | 6 | 25 |
| 4 | A. Asteras | 14 | 8 | 1 | 5 | 23:21 | 2 | 25 |
| 5 | Makedonikos | 14 | 6 | 6 | 2 | 27:10 | 17 | 24 |
| 6 | Plagia | 14 | 6 | 4 | 4 | 20:12 | 8 | 22 |
| 7 | AS Giannitsa | 14 | 7 | 1 | 6 | 23:15 | 8 | 22 |
| 8 | M. Alexandros Trikala | 14 | 6 | 3 | 5 | 20:18 | 2 | 21 |
| 9 | Edessaikos | 14 | 6 | 3 | 5 | 16:19 | -3 | 21 |
| 10 | Niki Agkathia | 14 | 6 | 2 | 6 | 15:16 | -1 | 20 |
| 11 | Nea Kallikrateia | 14 | 4 | 3 | 7 | 15:20 | -5 | 15 |
| 12 | Aetos Varvaras | 14 | 4 | 2 | 8 | 21:27 | -6 | 14 |
| 13 | Ethnikos Giannitsa | 14 | 3 | 2 | 9 | 17:26 | -9 | 11 |
| 14 | PAO Koufalion | 14 | 1 | 5 | 8 | 8:22 | -14 | 8 |
| 15 | PAOK Alexandreia | 14 | 1 | 1 | 12 | 11:45 | -34 | 4 |
Promotion ~ Gamma Ethniki ~ Promotion Play~offs (Promotion ~ Play Offs: )
Relegation
2020/21 Promotion - Play Offs
North
| Pl | W | D | L | Diff | Pts | |||
| 1 | Karditsa | 4 | 3 | 1 | 0 | 9:4 | 5 | 10 |
| 2 | Orfeas Xanthi | 4 | 2 | 1 | 1 | 4:3 | 1 | 7 |
| 3 | Acheron Kanalaki | 4 | 2 | 0 | 2 | 8:5 | 3 | 6 |
| 4 | Poseidonas Michanionas | 4 | 1 | 2 | 1 | 4:5 | -1 | 5 |
| 5 | Dia. Stefanovik | 4 | 0 | 0 | 4 | 2:10 | -8 | 0 |
South
| Pl | W | D | L | Diff | Pts | |||
| 1 | Kifisias | 4 | 4 | 0 | 0 | 8:0 | 8 | 12 |
| 2 | Irodotos | 4 | 2 | 1 | 1 | 3:3 | 0 | 7 |
| 3 | Panionios | 4 | 2 | 0 | 2 | 3:3 | 0 | 6 |
| 4 | Zakynthos | 4 | 1 | 0 | 3 | 3:7 | -4 | 3 |
| 5 | Thyella D | 4 | 0 | 1 | 3 | 1:5 | -4 | 1 |
Promotion ~ Football League
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