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Promotion ~ Gamma Ethniki ~ Promotion Play~offs (Promotion ~ Play Offs: )
Relegation
North
South
Promotion ~ Football League
2020/21 Main
| Pl | W | D | L | Diff | Pts | |||
| 1 | Karditsa | 14 | 12 | 2 | 0 | 40:5 | 35 | 38 |
| 2 | Karitsa | 14 | 11 | 2 | 1 | 28:7 | 21 | 35 |
| 3 | Ethnikos Neou | 14 | 8 | 1 | 5 | 16:17 | -1 | 25 |
| 4 | Aetos Makrychoriou | 14 | 7 | 3 | 4 | 24:11 | 13 | 24 |
| 5 | Kozani FC | 14 | 6 | 5 | 3 | 17:15 | 2 | 23 |
| 6 | Atromitos Palamas | 14 | 6 | 4 | 4 | 17:14 | 3 | 22 |
| 7 | Iraklis Larissa | 14 | 6 | 2 | 6 | 23:15 | 8 | 20 |
| 8 | Fikis | 14 | 6 | 2 | 6 | 22:17 | 5 | 20 |
| 9 | Elassona | 14 | 5 | 4 | 5 | 16:16 | 0 | 19 |
| 10 | Sellana | 14 | 5 | 1 | 8 | 15:15 | 0 | 16 |
| 11 | Dias Diou | 14 | 3 | 4 | 7 | 11:23 | -12 | 13 |
| 12 | Amyntaio | 14 | 3 | 3 | 8 | 12:36 | -24 | 12 |
| 13 | Meteora | 14 | 2 | 4 | 8 | 11:24 | -13 | 10 |
| 14 | Oikonomos | 14 | 2 | 3 | 9 | 14:29 | -15 | 9 |
| 15 | Makedonikos Foufas | 14 | 3 | 0 | 11 | 12:34 | -22 | 9 |
Promotion ~ Gamma Ethniki ~ Promotion Play~offs (Promotion ~ Play Offs: )
Relegation
2020/21 Promotion - Play Offs
North
| Pl | W | D | L | Diff | Pts | |||
| 1 | Karditsa | 4 | 3 | 1 | 0 | 9:4 | 5 | 10 |
| 2 | Orfeas Xanthi | 4 | 2 | 1 | 1 | 4:3 | 1 | 7 |
| 3 | Acheron Kanalaki | 4 | 2 | 0 | 2 | 8:5 | 3 | 6 |
| 4 | Poseidonas Michanionas | 4 | 1 | 2 | 1 | 4:5 | -1 | 5 |
| 5 | Dia. Stefanovik | 4 | 0 | 0 | 4 | 2:10 | -8 | 0 |
South
| Pl | W | D | L | Diff | Pts | |||
| 1 | Kifisias | 4 | 4 | 0 | 0 | 8:0 | 8 | 12 |
| 2 | Irodotos | 4 | 2 | 1 | 1 | 3:3 | 0 | 7 |
| 3 | Panionios | 4 | 2 | 0 | 2 | 3:3 | 0 | 6 |
| 4 | Zakynthos | 4 | 1 | 0 | 3 | 3:7 | -4 | 3 |
| 5 | Thyella D | 4 | 0 | 1 | 3 | 1:5 | -4 | 1 |
Promotion ~ Football League
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