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Group 1
Group 2
Promotion ~ Liga Premier Serie A (Apertura ~ Play Offs: )
Quarter-finals
Semi-finals
Final
Group 1
Group 2
Promotion ~ Liga Premier Serie A (Clausura ~ Play Offs: )
Quarter-finals
Semi-finals
Final
Final
2021/22 Apertura
Group 1
| Pl | W | WO | D | LO | L | Pts | |||
| 1 | Mazorqueros | 13 | 11 | 0 | 1 | 0 | 1 | 30:8 | 38 |
| 2 | Alacranes de Durango | 13 | 9 | 0 | 3 | 0 | 1 | 24:10 | 31 |
| 3 | Saltillo | 13 | 9 | 1 | 2 | 0 | 1 | 25:12 | 31 |
| 4 | Coras | 13 | 6 | 1 | 1 | 0 | 5 | 20:15 | 24 |
| 5 | Gavilanes de Matamoros | 13 | 7 | 0 | 1 | 1 | 4 | 20:15 | 24 |
| 6 | Tecos FC | 13 | 6 | 0 | 3 | 0 | 4 | 18:14 | 22 |
| 7 | Tritones Vallarta | 13 | 5 | 1 | 1 | 0 | 6 | 21:26 | 18 |
| 8 | Colima FC | 13 | 5 | 0 | 2 | 0 | 6 | 18:18 | 17 |
| 9 | Leones Negros 2 | 13 | 3 | 1 | 2 | 1 | 6 | 18:21 | 15 |
| 10 | Cimarrones de Sonora 2 | 13 | 4 | 0 | 1 | 1 | 7 | 20:20 | 14 |
| 11 | Correcaminos 2 | 13 | 3 | 0 | 3 | 0 | 7 | 13:18 | 12 |
| 12 | UA Zacatecas | 13 | 3 | 0 | 2 | 0 | 8 | 19:26 | 12 |
| 13 | Catedraticos Elite | 13 | 3 | 0 | 1 | 1 | 8 | 13:28 | 11 |
| 14 | Mineros de Fresnillo | 13 | 1 | 0 | 1 | 0 | 11 | 7:35 | 4 |
Group 2
| Pl | W | WO | D | LO | L | Pts | |||
| 1 | Cafetaleros | 12 | 10 | 0 | 1 | 0 | 1 | 31:8 | 35 |
| 2 | Inter Playa Del Carmen | 12 | 8 | 0 | 3 | 0 | 1 | 36:8 | 30 |
| 3 | Reboceros de La Piedad | 12 | 7 | 0 | 3 | 0 | 2 | 20:8 | 29 |
| 4 | Yalmakan | 12 | 8 | 0 | 0 | 0 | 4 | 22:12 | 26 |
| 5 | Halcones de Zapopan | 12 | 7 | 0 | 0 | 0 | 5 | 21:18 | 22 |
| 6 | Inter de Queretaro | 12 | 4 | 0 | 4 | 0 | 4 | 11:8 | 17 |
| 7 | Canamy | 12 | 4 | 0 | 2 | 0 | 6 | 11:21 | 14 |
| 8 | Montaneses | 12 | 3 | 0 | 3 | 1 | 5 | 15:16 | 13 |
| 9 | Lobos ULMX | 12 | 3 | 0 | 2 | 1 | 6 | 17:20 | 13 |
| 10 | Dongu | 12 | 3 | 1 | 2 | 0 | 6 | 12:21 | 13 |
| 11 | Canoneros | 12 | 3 | 1 | 0 | 0 | 8 | 15:23 | 12 |
| 12 | Escorpiones | 12 | 3 | 0 | 1 | 0 | 8 | 15:25 | 11 |
| 13 | Leviatan | 12 | 2 | 0 | 1 | 0 | 9 | 8:46 | 7 |
Promotion ~ Liga Premier Serie A (Apertura ~ Play Offs: )
2021/22 Apertura - Play Offs
Quarter-finals
| 1 | Mazorqueros | Bye | |
| 2 | Alacranes de Durango | Saltillo | 1 : 0, 1 : 0 |
| 3 | Cafetaleros | Coras | 3 : 3, 2 : 0 |
| 4 | Inter Playa Del Carmen | Yalmakan | 3 : 1, 2 : 0 |
Semi-finals
| 1 | Mazorqueros | Alacranes de Durango | 0 : 2, 0 : 0 |
| 2 | Cafetaleros | Inter Playa Del Carmen | 3 : 2, 1 : 3 |
Final
| 1 | Alacranes de Durango | Inter Playa Del Carmen | 0 : 0, 1 : 0 |
2021/22 Clausura
Group 1
| Pl | W | WO | D | LO | L | Pts | |||
| 1 | Mazorqueros | 13 | 9 | 0 | 3 | 1 | 0 | 30:10 | 34 |
| 2 | Tritones Vallarta | 13 | 8 | 1 | 1 | 0 | 3 | 23:12 | 31 |
| 3 | Alacranes de Durango | 13 | 7 | 0 | 5 | 0 | 1 | 32:11 | 29 |
| 4 | Coras | 13 | 7 | 0 | 3 | 1 | 2 | 20:12 | 26 |
| 5 | Saltillo | 13 | 8 | 0 | 1 | 0 | 4 | 24:18 | 26 |
| 6 | Cimarrones de Sonora 2 | 13 | 5 | 0 | 3 | 0 | 5 | 19:15 | 20 |
| 7 | Gavilanes de Matamoros | 13 | 3 | 1 | 7 | 0 | 2 | 14:9 | 19 |
| 8 | UA Zacatecas | 13 | 3 | 1 | 4 | 1 | 4 | 22:20 | 17 |
| 9 | Tecos FC | 13 | 3 | 2 | 4 | 0 | 4 | 13:19 | 17 |
| 10 | Leones Negros 2 | 13 | 3 | 0 | 3 | 1 | 6 | 13:22 | 13 |
| 11 | Colima FC | 13 | 2 | 1 | 3 | 0 | 7 | 11:21 | 11 |
| 12 | Mineros de Fresnillo | 13 | 1 | 1 | 4 | 1 | 6 | 17:29 | 11 |
| 13 | Correcaminos 2 | 13 | 2 | 0 | 2 | 0 | 9 | 10:29 | 9 |
| 14 | Catedraticos Elite | 13 | 0 | 0 | 3 | 2 | 8 | 9:30 | 5 |
Group 2
| Pl | W | WO | D | LO | L | Pts | |||
| 1 | Inter Playa Del Carmen | 12 | 9 | 0 | 2 | 0 | 1 | 31:9 | 31 |
| 2 | Cafetaleros | 12 | 8 | 0 | 4 | 0 | 0 | 31:6 | 29 |
| 3 | Yalmakan | 12 | 7 | 0 | 3 | 0 | 2 | 15:4 | 27 |
| 4 | Escorpiones | 12 | 7 | 0 | 0 | 0 | 5 | 22:21 | 23 |
| 5 | Montaneses | 12 | 6 | 0 | 2 | 0 | 4 | 19:12 | 22 |
| 6 | Halcones de Zapopan | 12 | 6 | 0 | 1 | 0 | 5 | 22:17 | 21 |
| 7 | Canamy | 12 | 5 | 0 | 3 | 0 | 4 | 17:14 | 20 |
| 8 | Reboceros de La Piedad | 12 | 5 | 0 | 3 | 0 | 4 | 21:12 | 19 |
| 9 | Lobos ULMX | 12 | 5 | 0 | 3 | 0 | 4 | 11:12 | 18 |
| 10 | Canoneros | 12 | 4 | 0 | 1 | 0 | 7 | 10:25 | 14 |
| 11 | Inter de Queretaro | 12 | 1 | 1 | 2 | 0 | 8 | 6:27 | 7 |
| 12 | Dongu | 12 | 2 | 0 | 0 | 0 | 10 | 15:29 | 6 |
| 13 | Leviatan | 12 | 0 | 0 | 0 | 1 | 11 | 6:38 | 1 |
Promotion ~ Liga Premier Serie A (Clausura ~ Play Offs: )
2021/22 Clausura - Play Offs
Quarter-finals
| 1 | Yalmakan | Tritones Vallarta | 1 : 1, 0 : 1 |
| 2 | Escorpiones | Mazorqueros | 0 : 7, 1 : 2 |
| 3 | Alacranes de Durango | Cafetaleros | 1 : 2, 1 : 1 |
| 4 | Coras | Inter Playa Del Carmen | 1 : 1, 1 : 2 |
Semi-finals
| 1 | Tritones Vallarta | Mazorqueros | 1 : 1, 1 : 2 |
| 2 | Cafetaleros | Inter Playa Del Carmen | 1 : 0, 0 : 0 |
Final
| 1 | Mazorqueros | Cafetaleros | 1 : 0, 0 : 0 |
2021/22 Play Offs
Final
| 1 | Alacranes de Durango | Mazorqueros | 4 : 2, 1 : 0 |
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