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Promotion ~ Premier League
Relegation
2021/22
| Pl | W | D | L | Diff | Pts | |||
| 1 | Metalist Kharkiv | 20 | 17 | 2 | 1 | 52:9 | 43 | 53 |
| 2 | Kryvbas | 20 | 12 | 6 | 2 | 38:17 | 21 | 42 |
| 3 | Alliance | 19 | 10 | 3 | 6 | 33:24 | 9 | 33 |
| 4 | Obolon | 19 | 10 | 3 | 6 | 24:16 | 8 | 33 |
| 5 | Nyva Ternopil | 20 | 8 | 5 | 7 | 22:22 | 0 | 29 |
| 6 | Hirnyk-Sport | 20 | 8 | 5 | 7 | 15:17 | -2 | 29 |
| 7 | Prykarpattya | 20 | 8 | 4 | 8 | 27:26 | 1 | 28 |
| 8 | Podillya Khmelnytskyi | 20 | 7 | 5 | 8 | 19:18 | 1 | 26 |
| 9 | Zhytomyr | 18 | 7 | 4 | 7 | 21:17 | 4 | 25 |
| 10 | Volyn Lutsk | 19 | 6 | 7 | 6 | 17:20 | -3 | 25 |
| 11 | Olimpik Donetsk | 19 | 7 | 2 | 10 | 19:23 | -4 | 23 |
| 12 | Kramatorsk | 18 | 7 | 1 | 10 | 16:24 | -8 | 22 |
| 13 | Ahrobiznes Volochysk | 20 | 4 | 9 | 7 | 16:23 | -7 | 21 |
| 14 | VPK-Agro | 20 | 5 | 3 | 12 | 16:28 | -12 | 18 |
| 15 | Uzhhorod | 20 | 4 | 4 | 12 | 16:40 | -24 | 16 |
| 16 | Kremin | 20 | 4 | 1 | 15 | 16:43 | -27 | 13 |
| 17 | Mykolaiv | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| 18 | Minaj | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
Promotion ~ Premier League
Relegation
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