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1/32-finals
1/16-finals
1/8-finals
Quarter-finals
Semi-finals
Final
Semi-finals
Final
2021 Singles - Main
1/32-finals
| 1 | Thiem D. (1) | Bye | |
| 2 | O'Connell C. (Q) | Harris L. (Q) | 1 : 2 |
| 3 | Davidovich Fokina A. | Albot R. (LL) | 2 : 0 |
| 4 | Bye | Krajinovic F. (14) | |
| 5 | Giustino L. (LL) | Bye | |
| 6 | Bhambri Y. (Q) | Bedene A. | 1 : 2 |
| 7 | Nishikori K. | Opelka R. | 2 : 1 |
| 8 | Bye | Goffin D. (5) | |
| 9 | Shapovalov D. (3) | Bye | |
| 10 | Struff J-L. | Kukushkin M. (Q) | 2 : 0 |
| 11 | Gasquet R. | Cecchinato M. | 2 : 0 |
| 12 | Bye | Hurkacz H. (13) | |
| 13 | De Minaur A. (9) | Bye | |
| 14 | Chardy J. | Ramos A. | 2 : 1 |
| 15 | Popyrin A. (WC) | Novak D. (WC) | 2 : 0 |
| 16 | Bye | Khachanov K. (8) | |
| 17 | Sonego L. (17) | Bye | |
| 18 | Zapata Miralles B. (Q) | Millman J. | 2 : 0 |
| 19 | Karatsev A. (WC) | Gerasimov E. | 2 : 0 |
| 20 | Bye | Evans D. (12) | |
| 21 | Sinner J. (16) | Bye | |
| 22 | Nishioka Y. | Bublik A. | 0 : 2 |
| 23 | Ebden M. (SE) | Bye | |
| 24 | Bye | Bautista-Agut R. (4) | |
| 25 | Carreno-Busta P. (6) | Bye | |
| 26 | Pospisil V. | Fucsovics M. | 1 : 2 |
| 27 | Jaziri M. (WC) | Tsonga J-W. (RET.) | 0 : 0 |
| 28 | Bye | Lajovic D. (11) | |
| 29 | Fritz T. (15) | Bye | |
| 30 | Basilashvili N. | Bye | |
| 31 | Ruusuvuori E. (Q) | Thompson J. | 2 : 0 |
| 32 | Bye | Rublev A. (2) |
1/16-finals
1/8-finals
Quarter-finals
| 1 | Harris L. | Nishikori K. | 2 : 1 |
| 2 | Shapovalov D. (3) | Chardy J. | 2 : 0 |
| 3 | Karatsev A. | Sinner J. (16) | 2 : 1 |
| 4 | Fucsovics M. | Rublev A. (2) | 0 : 2 |
Semi-finals
| 1 | Harris L. | Shapovalov D. (3) | 2 : 1 |
| 2 | Karatsev A. | Rublev A. (2) | 2 : 1 |
Final
| 1 | Harris L. | Karatsev A. | 0 : 2 |
2021 Singles - Qualification
Semi-finals
Final
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